UCSF adopts Magseed as care standard for localizing impalpable breast lesions

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New Magseed technology guides surgeons during cancer care to simplify treatment, improve patient experience.

Endomag, the cancer healthcare company, announced today that the University of California, San Francisco (UCSF) has become the first U.S. site to adopt Magseed as its standard of care for localization of impalpable breast lesions. Magseed is a simpler, more effective alternative to traditional wire localization methods.

Breast cancer is the most common form of cancer in women, with 1.7 million new cases of breast cancer globally every year. This number is expected to double by 2030. Due to a rise in national screening programs and an increase in public awareness, breast cancer is being caught at earlier stages. This means that the tumors are smaller, less defined and harder to feel, with up to 50% of all breast tumors impalpable at the time of diagnosis. In these cases, a technique called wire localization is typically used by surgeons to locate the tumor.

Although widely used, wire localization can cause complications. On average 1 in every 4 breast wire localizations result in cancerous tissue being left behind, or require additional surgery because the wire became dislodged between its implantation and surgical removal. Additionally, there is a risk of infection due to the wire protruding from the skin, so the placement of the wire must be done on the same day as surgery. These issues result in unnecessary anxiety for patients, delays to the surgical lists and fewer patients being treated.

Dr. Eric Mayes, CEO of Endomag noted “The wire localization technique has remained largely the same since it was introduced over 30 years ago and it causes a lot of anxiety for patients. We wanted to create a technique that could simplify the localization process and improve the patient experience.”

Magseed is smaller than a grain of rice and can be placed into the tumor for up to 30 days, allowing the patient to return home ahead of surgery. Once implanted, the seed is not easily dislodged and patients are not restricted in movement or activity. During surgery, the seed is detected with the Sentimag probe to guide accurate removal of the tumor and maximize the amount of healthy tissue left behind. Unlike radioactive alternatives that involve strict regulatory oversight and complex logistics, the Magseed technique can be widely adopted by any hospital, regardless of size.

Dr. Laura Esserman (Breast Surgeon, UCSF): “We are excited to have a set of safe, easy-to-use tools that will improve the efficiency of identifying breast lesions and dramatically improve the experience of patients and clinicians, as well as the workflow in the operating room.”

Dr. Michael Alvarado (Breast Surgeon, UCSF): “We have been looking for a better alternative to wire localization for some time, as the wire procedure adds additional stress for the patients on the day of surgery and often causes delays to our operating schedule. Very early in our evaluation of the magnetic seed technique we found that we could avoid a same-day placement, and the surgeries could be completed in less time, without compromising accuracy. This offers a tangible benefit to both our clinical team and, most importantly, our patients.”

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